CATALYSIS OF A DISFAVORED REACTION: AN ANTIBODY EXO DIELS-ALDERASE-TSA-INHIBITOR COMPLEX AT 1.95 A RESOLUTION


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B-Cell Epitope
Epitope  
   
Complex PDB ID 1A3L
Accession Number 3DIEP0002
IEDB ID Not available.
Epitope Sequence 1-Carboxy-1 -[(Dimethylamino)-Carbonyl]Ferrocene
Starting Position213
Ending Position213
Epitope Type Non peptidic

Assay Information  
Assay Antigen Not available
PDB CategoryIMMUNOGLOBULIN
Keyword DIELS-ALDER; DISFAVORED REACTION; CATALYTIC ANTIBODY; IMMUNOGLOBULIN
Antibody Residues Interacting with Antigen Open in new window      Download dimplot pdb file
Antibody Chain 1 PDB Chain H
Antibody Chain 2 PDB ChainL
Antigen PDB ChainL
CommentsNot available

Experimental Details
Method
X-RAY DIFFRACTION
Resolution
1.95
R-Value
0.184
Space Group
C 1 2 1
Unit Cell
Length(Å) Angle(°)
a = 182.9 α = 90
b = 40.5 β = 109
c = 67.7 γ = 90


Source Information  
Structure Determination Method X-RAY DIFFRACTION
Source Organism Mus musculus
Common Namehouse mouse
Taxonomic ID10090
Source Organism Mus musculus
Common Namehouse mouse
Taxonomic ID10090
Entity ID2

Ligand non-polymer
Ligand Name1-CARBOXY-1'-[(DIMETHYLAMINO)-CARBONYL]FERROCENE
Chem Name CFC




Sequence
Protein Name
1-CARBOXY-1'-[(DIMETHYLAMINO)-CARBONYL]FERROCENE
Poly type
polypeptide(L)
Sequence status
Complete

Err:Conn