HUMANIZED ANTI-LYSOZYME FV COMPLEXED WITH LYSOZYME


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B-Cell Epitope
Epitope  
   
Complex PDB ID 1BVK
Accession Number 3DIEP0237
IEDB ID 136909
Epitope Sequence D36; N37; G40; S42; N45; G120; G135; D137; V138; Q139; L147
Starting Position36-37,40,42,45,120,135,137-139,147
Ending Position147
Epitope Type Discontinuous Epitope

Assay Information  
Assay Antigen Lysozyme C precursor Gallus gallus
PDB CategoryCOMPLEX (HUMANIZED ANTIBODY/HYDROLASE)
Keyword HUMANIZED ANTIBODY; ANTIBODY COMPLEX; FV; ANTI-LYSOZYME; COMPLEX (HUMANIZED ANTIBODY/HYDROLASE)
Antibody Residues Interacting with Antigen Open in new window      Download dimplot pdb file
Antibody Chain 1 PDB Chain B
Antibody Chain 2 PDB ChainA
Antigen PDB ChainC
Contact Area for Antigen 715.7
Contact Area for Antibody689.2
CommentsThe epitope recognized by humanized HuLys Fv fragment on lysozyme was determined from the complex by X-ray diffraction and molecular replacement solution.

Experimental Details
Method
X-RAY DIFFRACTION
Resolution
2.7
R-Value
0.208
Space Group
P 41 21 2
Unit Cell
Length(Å) Angle(°)
a = 97.7 α = 90
b = 97.7 β = 90
c = 174.9 γ = 90


Source Information  
Structure Determination Method X-RAY DIFFRACTION

Ligand




Sequence
Protein Name
HUMANIZED ANTI-LYSOZYME FV COMPLEXED WITH LYSOZYME
Poly type
polypeptide(L)
Sequence status
Complete

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