CRYSTAL STRUCTURE OF THE MURINE CLASS II ALLELE I-A(G7) COMPLEXED WITH THE GLUTAMIC ACID DECARBOXYLASE (GAD65) PEPTIDE 207-220


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MHC-Binding
Epitope  
   
Complex PDB ID 1ES0
Accession Number 3DIEP0397
IEDB ID 73674
Epitope Sequence YEIAPVFVLLEYVT
Starting Position207
Ending Position220
Epitope Type Linear Epitope

Assay Information  
Assay Antigen Purified MHC - X-ray crystallography Structure (crystal; NMR; etc.)
PDB CategoryIMMUNE SYSTEM
Keyword HISTOCOMPATIBILITY ANTIGEN; CLASS II MHC I-A(G7); IMMUNE SYSTEM
Antibody Residues Interacting with Antigen Open in new window      Download dimplot pdb file
Antibody Chain 1 PDB Chain A
Antigen PDB ChainB
CommentsThe epitope is covalently linked to the ?-chain of the MHC at the C-terminal.

Experimental Details
Method
X-RAY DIFFRACTION
Resolution
2.6
R-Value
0.21
Space Group
C 2 2 21
Unit Cell
Length(Å) Angle(°)
a = 95.149 α = 90
b = 110.123 β = 90
c = 96.084 γ = 90



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Source Information  
Structure Determination Method X-RAY DIFFRACTION