CRYSTAL STRUCTURE OF AN ANTI-CARBOHYDRATE ANTIBODY DIRECTED AGAINST VIBRIO CHOLERAE O1 IN COMPLEX WITH ANTIGEN


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B-Cell Epitope
Epitope  
   
Complex PDB ID 1F4Y
Accession Number 3DIEP0037
IEDB ID 133965
Epitope Sequence H: (MGU)301
Starting Position301
Ending Position301
Epitope Type Non peptidic

Assay Information  
Assay Antigen 4;6-dideoxy-4-(3-deoxy-L-glycero-tetronamido)-alpha-D-Manp2Me-(1->2)-4;6-dideoxy-4-(3-deoxy-L-glycero-tetronamido)-alpha-D-Manp lipopolysaccharide Vibrio cholerae O1 serotype Ogawa
PDB CategoryIMMUNE SYSTEM
Keyword anti-carbohydrate antibody; IMMUNE SYSTEM
Antibody Residues Interacting with Antigen Open in new window      Download dimplot pdb file
Antibody Chain 1 PDB Chain L
Antibody Chain 2 PDB ChainH
Antigen PDB ChainH
Contact Area for Antigen 394.2
Contact Area for Antibody251.7
CommentsNo comment.

Experimental Details
Method
X-RAY DIFFRACTION
Resolution
2.8
R-Value
Space Group
P 1 21 1
Unit Cell
Length(Å) Angle(°)
a = 40.69 α = 90
b = 113.36 β = 93.93
c = 45.58 γ = 90



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Source Information  
Structure Determination Method X-RAY DIFFRACTION
Source Organism Mus musculus
Common Namehouse mouse
Taxonomic ID10090
Source Organism Mus musculus
Common Namehouse mouse
Taxonomic ID10090
Entity ID2


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Ligand non-polymer