MURINE T-CELL RECEPTOR VARIABLE DOMAIN/FAB COMPLEX


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B-Cell Epitope
Epitope  
   
Complex PDB ID 1KB5
Accession Number 3DIEP0212
IEDB ID 114710
Epitope Sequence A: Q1; Q2; D26; Y93; Q94; G95; G96; R97; A98 B: W32; Q43; Q45; W46; R51; S52; D55; E57; K59; S60; L61; P62; P97; W99
Starting Position1-2,26,93
Ending Position98
Epitope Type Discontinuous Epitope

Assay Information  
Assay Antigen KB5-C20 TCR Mus musculus
PDB CategoryCOMPLEX (IMMUNOGLOBULIN/RECEPTOR)
Keyword T-CELL RECEPTOR; STRAND SWITCH; FAB; ANTICLONOTYPIC; (IMMUNOGLOBULIN/RECEPTOR); COMPLEX (IMMUNOGLOBULIN/RECEPTOR) COMPLEX
Antibody Residues Interacting with Antigen Open in new window      Download dimplot pdb file
Antibody Chain 1 PDB Chain H
Antibody Chain 2 PDB ChainL
Antigen PDB ChainA
Contact Area for Antigen 1164.7
Contact Area for Antibody1154
CommentsThe areas of the buried surfaces on the TCR Va domain is 545 (22 residues) and on the Vß domain is 833 (26 residues).The epitope and paratope residues and details of contacts are not provided in the reference.

Experimental Details
Method
X-RAY DIFFRACTION
Resolution
2.5
R-Value
0.221
Space Group
P 21 21 2
Unit Cell
Length(Å) Angle(°)
a = 187.31 α = 90
b = 80.95 β = 90
c = 52.08 γ = 90



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Source Information  
Structure Determination Method X-RAY DIFFRACTION
Source Organism Mus musculus
Common Namehouse mouse
Taxonomic ID10090
Source Organism Mus musculus
Common Namehouse mouse
Taxonomic ID10090
Entity ID4


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Ligand non-polymer