INFLUENZA VIRUS HEMAGGLUTININ COMPLEXED WITH AN ANTIBODY THAT PREVENTS THE HEMAGGLUTININ LOW PH FUSOGENIC TRANSITION


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B-Cell Epitope
Epitope  
   
Complex PDB ID 1KEN
Accession Number 3DIEP0071
IEDB ID 104374
Epitope Sequence T142; T144; S152; N153; W169; G174; S175; P178; V179; N181; S202; T203; Q205; E206; S209; G241; L242
Starting Position142,144,152-153,169,174-175,178-179,181,202-203,205-206,209,241
Ending Position242
Epitope Type Discontinuous Epitope

Assay Information  
Assay Antigen QDLPGNDNSTATLCL GHHAVPNGTLVKTIT DDQIEVTNATELVQS SSTGK… Hemagglutinin precursor (17-520) Influenza A virus (A/X-31(H3N2))
PDB CategoryViral protein/Immune system
Keyword HEMAGGLUTININ; ENVELOPE PROTEIN; GLYCOPROTEIN; Viral protein/Immune system COMPLEX
Antibody Residues Interacting with Antigen Open in new window      Download dimplot pdb file
Antibody Chain 1 PDB Chain H
Antibody Chain 2 PDB ChainL
Antigen PDB ChainA
Contact Area for Antigen 1008.1
Contact Area for Antibody1039.4
CommentsNot available

Experimental Details
Method
X-RAY DIFFRACTION
Resolution
3.5
R-Value
Space Group
P 21 21 2
Unit Cell
Length(Å) Angle(°)
a = 143.041 α = 90
b = 315.588 β = 90
c = 97.029 γ = 90



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Source Information  
Structure Determination Method X-RAY DIFFRACTION
Source Organism Influenza A virus (A/X-31(H3N2))
Taxonomic ID132504
Source Organism Influenza A virus (A/X-31(H3N2))
Taxonomic ID132504
Source Organism Mus musculus
Common Namehouse mouse
Taxonomic ID10090
Source Organism Mus musculus
Common Namehouse mouse
Taxonomic ID10090
Entity ID4


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Ligand D-saccharide