2C/H-2KBM3/DEV8 ALLOGENEIC COMPLEX


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T-Cell Epitope
Epitope  
   
Complex PDB ID 1MWA
Accession Number 3DIEP0308
IEDB ID 100016
Epitope Sequence EQYKFYSV
Starting Position1
Ending Position8
Epitope Type Linear Epitope

Assay Information  
Assay Antigen EQYKFYSV NADH dehydrogenase (ubiquinone) 1 alpha subcomplex; 4 (61-68) Mus musculus
PDB CategoryIMMUNE SYSTEM
Keyword Ig domain; antigen recognition; complementarity determining region; IMMUNE SYSTEM
Antibody Residues Interacting with Antigen Open in new window      Download dimplot pdb file
Antibody Chain 1 PDB Chain A
Antigen PDB ChainP
CommentsThe crystal structure of the ternary complex of the 2C TCR with the epitope bound to allogenic H-2-Kbm3 was determined. There are two molecules in the crystallographic asymmetric unit. PDB chains for each complex are: Complex I: MHC ?-chain: H; ?2-m chain: L; epitope chain: P; TCR ?-chain: A; TCR ?-chain: B. Complex II: MHC ?-chain: I; ?2-m chain: M; epitope chain: Q; TCR ?-chain: C; TCR ?-chain: D. The second complex is highly disordered; therefore only the first one was curated. PDB 1MWA supersedes 1JTR.

Experimental Details
Method
X-RAY DIFFRACTION
Resolution
2.4
R-Value
0.28543
Space Group
P 21 21 2
Unit Cell
Length(Å) Angle(°)
a = 297.899 α = 90
b = 95.942 β = 90
c = 84.735 γ = 90



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Source Information  
Structure Determination Method X-RAY DIFFRACTION