TCR/HLA-DR2b/MBP-peptide complex


Tab-View Sample


T-Cell Epitope
Epitope  
   
Complex PDB ID 1YMM
Accession Number 3DIEP0281
IEDB ID 13572
Epitope Sequence ENPVVHFFKNIVTPR
Starting Position85
Ending Position98
Epitope Type Linear Epitope

Assay Information  
Assay Antigen ENPVVHFFKNIVTPR MBP Homo sapiens
PDB CategoryIMMUNE SYSTEM
Keyword protein-protein complex; T cell repertoire; auto-immunity; IMMUNE SYSTEM
Antibody Residues Interacting with Antigen Open in new window      Download dimplot pdb file
Antibody Chain 1 PDB Chain D
Antigen PDB ChainC
CommentsThe crystal structure contains the MHC/epitope complex bound to TCR Ob.1A12. The epitope molecule was covalently linked to the N-terminus of the TCR? chain through a flexible linker. No electron density was observed for the residues of the linker sequence and for the C-terminal residue of the epitope (Arg).

Experimental Details
Method
X-RAY DIFFRACTION
Resolution
3.5
R-Value
0.276
Space Group
F 2 2 2
Unit Cell
Length(Å) Angle(°)
a = 137.34 α = 90
b = 212.62 β = 90
c = 278.22 γ = 90



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Source Information  
Structure Determination Method X-RAY DIFFRACTION