THE STRUCTURE OF AN INTERMEDIATE IN CLASS II MHC MATURATION: CLIP BOUND TO HLA-DR3


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MHC-Binding
Epitope  
   
Complex PDB ID 1A6A
Accession Number 3DIEP0395
IEDB ID 38564
Epitope Sequence PVSKMRMATPLLMQA
Starting Position87
Ending Position101
Epitope Type Linear Epitope

Assay Information  
Assay Antigen Purified MHC - X-ray crystallography Structure (crystal; NMR; etc.)
PDB CategoryCOMPLEX (TRANSMEMBRANE/GLYCOPROTEIN)
Keyword MHC GLYCOPROTEIN; COMPLEX (TRANSMEMBRANE/GLYCOPROTEIN)
Antibody Residues Interacting with Antigen Open in new window      Download dimplot pdb file
Antibody Chain 1 PDB Chain A
Antigen PDB ChainC
CommentsResidues PVSKMRMATPLLMQA are the region observed in the crystal structure. N- and C-terminal residues in the peptide are disordered and not observable in the crystal structure.

Experimental Details
Method
X-RAY DIFFRACTION
Resolution
2.75
R-Value
0.246
Space Group
P 32 1 2
Unit Cell
Length(Å) Angle(°)
a = 78.45 α = 90
b = 78.45 β = 90
c = 159.1 γ = 120



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Source Information  
Structure Determination Method X-RAY DIFFRACTION