X-RAY CRYSTAL STRUCTURE OF HLA-DR4 COMPLEXED WITH PEPTIDE AND SEB


Tab-View Sample


MHC-Binding
Epitope  
   
Complex PDB ID 1D5M
Accession Number 3DIEP0458
IEDB ID 94970
Epitope Sequence XRAMXSX
Starting Position803
Ending Position810
Epitope Type Linear Epitope

Assay Information  
Assay Antigen "Purified MHC - X-ray crystallography Structure (crystal; NMR; etc.)"
PDB CategoryIMMUNE SYSTEM
Keyword COMPLEX (MHC CLASS II/SUPERANTIGEN); IMMUNE SYSTEM
Antibody Residues Interacting with Antigen Open in new window      Download dimplot pdb file
Antibody Chain 1 PDB Chain A
Antigen PDB ChainD
CommentsThe crystal structure contains the MHC/epitope complex bound to the superantigen (SAG) staphylococcal enterotoxin B (SEB). SAG PDB chain is D. The SAG was included in the complex as a vehicle to form crystals of MHC with novel compounds that diffract well. Clear electron density is observed for the MHC residues except for a loop consisting of residues B:105-112 and for the SAG molecule for a loop consisting of residues 99-108.

Experimental Details
Method
X-RAY DIFFRACTION
Resolution
2
R-Value
0.236
Space Group
P 21 21 21
Unit Cell
Length(Å) Angle(°)
a = 82.38 α = 90
b = 93.34 β = 90
c = 99.68 γ = 90



Fatal error: Uncaught Error: Call to undefined function mysql_connect() in /opt/lampp/htdocs/sedb/htdocs/tabview.php:6804 Stack trace: #0 {main} thrown in /opt/lampp/htdocs/sedb/htdocs/tabview.php on line 6804
Source Information  
Structure Determination Method X-RAY DIFFRACTION