CRYSTAL STRUCTURE OF THE HUMAN CLASS II MHC PROTEIN HLA-DR1 COMPLEXED WITH AN INFLUENZA VIRUS PEPTIDE


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MHC-Binding
Epitope  
   
Complex PDB ID 1DLH
Accession Number 3DIEP0345
IEDB ID 30016
Epitope Sequence PKYVKQNTLKLAT
Starting Position306
Ending Position318
Epitope Type Linear Epitope

Assay Information  
Assay Antigen "Purified MHC - X-ray crystallography Structure (crystal; NMR; etc.)"
PDB CategoryHISTOCOMPATIBILITY ANTIGEN
Keyword HISTOCOMPATIBILITY ANTIGEN
Antibody Residues Interacting with Antigen Open in new window      Download dimplot pdb file
Antibody Chain 1 PDB Chain A
Antigen PDB ChainC
CommentsAmongst MHC residues interacting with peptide; the residues that do not directly contact the peptide but are inaccessible to solvent are listed as well (residues of the chain A: I7; A61; and chain B: L26; C30; V38; K65; T77). Hydrogen bonds between MHC and only the peptide main chain are provided in the paper.

Experimental Details
Method
X-RAY DIFFRACTION
Resolution
R-Value
0.205
R-Free
0.304
Space Group
P 43 21 2
Unit Cell
Length(Å) Angle(°)
a = 94.6 α = 90
b = 94.6 β = 90
c = 247.5 γ = 90



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Source Information  
Structure Determination Method X-RAY DIFFRACTION