STRUCTURE OF CD40L IN COMPLEX WITH THE FAB FRAGMENT OF HUMANIZED 5C8 ANTIBODY


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B-Cell Epitope
Epitope  
   
Complex PDB ID 1I9R
Accession Number 3DIEP0056
IEDB ID 77425
Epitope Sequence A: E129; A130; S132; E142; K143; G144; Y146; C178; C218; S245; Q246; S248; H249; G250
Ending Position129-130,132,142-144,146,178,218,245-426,248-250
Epitope Type Discontinuous Epitope

Assay Information  
Assay Antigen CD40 ligand Homo sapiens
PDB CategoryCYTOKINE/IMMUNE SYSTEM
Keyword beta-sheet sandwich; immunoglobulin; CYTOKINE/IMMUNE SYSTEM COMPLEX
Antibody Residues Interacting with Antigen Open in new window      Download dimplot pdb file
Antibody Chain 1 PDB Chain L
Antibody Chain 2 PDB ChainH
Antigen PDB ChainA
CommentsNot available

Experimental Details
Method
X-RAY DIFFRACTION
Resolution
3.1
R-Value
0.233
Space Group
C 1 2 1
Unit Cell
Length(Å) Angle(°)
a = 224.48 α = 90
b = 129.91 β = 109.6
c = 96.49 γ = 90



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Source Information  
Structure Determination Method X-RAY DIFFRACTION
Source Organism Homo sapiens
Common Namehuman
Taxonomic ID9606
Source Organism Homo sapiens
Common Namehuman
Taxonomic ID9606
Source Organism Homo sapiens
Common Namehuman
Taxonomic ID9606
Source Organism Homo sapiens
Common Namehuman
Taxonomic ID9606
Entity ID3


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Ligand non-polymer