STRUCTURE OF A SINGLE-CHAIN FV FRAGMENT COMPLEXED WITH A CARBOHYDRATE ANTIGEN AT 1.7 ANGSTROMS RESOLUTION


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B-Cell Epitope
Epitope  
   
Complex PDB ID 1MFA
Accession Number 3DIEP0144
IEDB ID 127517
Epitope Sequence alpha-D-Galp-(1->2)-[alpha-D-Abep-(1->3)]-alpha-D-Manp
Starting Position337
Ending Position339
Epitope Type Non peptidic

Assay Information  
Assay Antigen alpha-D-Galp-(1->2)-[alpha-D-Abep-(1->3)]-alpha-D-Manp lipopolysaccharide Salmonella enterica subsp. enterica serovar Essen
PDB CategoryIMMUNOGLOBULIN
Keyword IMMUNOGLOBULIN
Antibody Residues Interacting with Antigen Open in new window      Download dimplot pdb file
Antibody Chain 1 PDB Chain L
Antibody Chain 2 PDB ChainH
Antigen PDB ChainH
Contact Area for Antigen 358.4
Contact Area for Antibody246.1
CommentsSe155-4 scFv is specific for an oligosaccharide epitope of Salmonella serogroup B LPS. The antigen was syntesized with an O-methyl group to preserve the alpha isomer of the anomeric carbon at terminal Mannose.

Experimental Details
Method
X-RAY DIFFRACTION
Resolution
1.7
R-Value
0.166
Space Group
P 21 21 21
Unit Cell
Length(Å) Angle(°)
a = 53.1 α = 90
b = 61 β = 90
c = 74.8 γ = 90


Source Information  
Structure Determination Method X-RAY DIFFRACTION


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Ligand
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