ANTIBODY MULTISPECIFICITY MEDIATED BY CONFORMATIONAL DIVERSITY


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B-Cell Epitope
Epitope  
   
Complex PDB ID 1OAY
Accession Number 3DIEP0134
IEDB ID 116184
Epitope Sequence Furazolidone
Starting Position122
Ending Position122
Epitope Type Non peptidic

Assay Information  
Assay Antigen Furazolidone
PDB CategoryIMMUNE SYSTEM
Keyword IMMUNE SYSTEM; ANTIBODY/COMPLEX; ANTIBODY; ALLERGY; IGE; CONFORMATIONAL DIVERSITY; MULTISPECIFICITY
Antibody Residues Interacting with Antigen Open in new window      Download dimplot pdb file
Antibody Chain 1 PDB Chain L
Antibody Chain 2 PDB ChainH
Antigen PDB ChainH
Contact Area for Antigen 297.5
Contact Area for Antibody165.2
CommentsThe antibody bound to this antigen has different conformation in unbound states [PDB: 1OAQ; 1OCW] and protein-bound state [PDB: 1OAZ]; but has the same conformation while bound to other two haptens [PDB: 1OAU; 1OAR].

Experimental Details
Method
X-RAY DIFFRACTION
Resolution
2.66
R-Value
0.226
Space Group
P 21 21 21
Unit Cell
Length(Å) Angle(°)
a = 79.174 α = 90
b = 79.142 β = 90
c = 168.91 γ = 90


Source Information  
Structure Determination Method X-RAY DIFFRACTION


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Ligand
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